Professor Gao’s research has focused on preclinical drug evaluation, traditional Chinese medicine pharmacology and toxicology, and the modernisation of traditional Chinese medicine compound prescriptions, with particular emphasis on military pharmacy for special environments. Over more than three decades of research, she has developed a technical framework for the safety evaluation of traditional Chinese medicine encompassing early toxicity prediction, toxic-substance analysis, and investigation of toxicity mechanisms, and established a key technology platform for traditional Chinese medicine safety evaluation that has been adopted by research institutions and pharmaceutical enterprises in China. Her work has addressed cross-tissue and cross-platform toxicogenomic prediction, the localisation and enrichment of trace toxic substances, and the rapid screening of interactions between nuclear receptors and drug-metabolising enzymes, contributing to the resolution of key technical challenges in the safety assessment of traditional Chinese medicine. She has authored more than 121 peer-reviewed publications as corresponding author in journals including Nature Communications, Signal Transduction and Targeted Therapy, and Chemical Engineering Journal, and holds 12 authorised invention patents. Her translational work has resulted in one Category 1.1 innovative drug certificate for military special-need traditional Chinese medicine, one Category 1.2 new drug certificate, and three production approvals. As first completer, she has received the National Science and Technology Progress Award (First Prize) and the National Science and Technology Progress Award (Second Prize). Through leadership of major national research programmes, including major projects of the National Natural Science Foundation of China and National Key Research and Development Programmes, Professor Gao has contributed to connecting traditional Chinese medicine with modern pharmacological and toxicological science, advancing the scientific basis for drug safety evaluation, military medical preparedness, and the modernisation of traditional Chinese medicine.