Professor He’s research has focused on international rivers, transboundary water resources, and ecological security in Asia, with particular emphasis on the hydrology, ecology, and human–environment interactions of the Mekong, Salween, Irrawaddy, and other transboundary river systems. Through extensive field investigations across the Tibetan Plateau and Southeast Asia, he has contributed to the understanding of hydrological regimes, sediment transport, and ecosystem dynamics in major Asian international rivers, as well as to the study of transboundary water cooperation and ecological risk assessment. His research has been supported by multiple major national research projects and international collaborative initiatives, integrating hydrogeographical analysis with questions of water-resource management and regional ecological security. He has authored numerous peer-reviewed publications and monographs and has led research programmes addressing the environmental and socio-economic dimensions of international river systems. Through sustained research and institutional leadership at Yunnan University, Professor He has contributed to the development of interdisciplinary approaches to international river studies and to broader scientific discussions on transboundary water governance, ecological security, and sustainable development in Asia.